Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Effects of Houttuynia cordata Thunb on Atherosclerosis and Lipidperoxidation in 2,3,7,8-TCDD-Damaged Rats

  • Kim, Hee-Jin (Department of Bioscience & Biotechnology, Silla University) ;
  • Lee, Sang-Hun (Department of Bioscience & Biotechnology, Silla University) ;
  • Lee, Jin-Young (Department of Bioscience & Biotechnology, Silla University) ;
  • Ha, Bae-Jin (Department of Bioscience & Biotechnology, Silla University)
  • Published : 2003.10.01
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Abstract

TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin), one of the notorious toxic environmental pollutants, damages various organs including liver and is regarded as an endocrine disrupter. To investigate the effects of Houttuynia cordata Thunb (HCT) on the biochemical parameters of function, liver and serum of TCDD-treated rats were used. After 7 days from TCDD (1 $\mu\textrm{g}$/kg) injection, HCT (200 mg/kg) was administered into rats intraperitoneally for 4 weeks. The lipidperoxide content was examined by measuring the level of total cholesterol, HDL-cholesterol, LDL-cholesterol, total lipid and triglyceride (TG) in serum, and malondialdehyde (MDA) in liver tissue of rats. (omitted)

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