Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Inhibitory Effect of Ginseng on Infection and Vacuolation of Helicobacter pylori

  • Kim, Jong-Mi (College of Pharmacy, Kyung Hee University) ;
  • Shin, Ji-Eun (Department of Food and Nutrition, Kyung Hee University) ;
  • Han, Myung-Joo (Department of Food and Nutrition, Kyung Hee University) ;
  • Choo, Min-Kyung (Department of Food and Nutrition, Kyung Hee University) ;
  • Park, Sung-Whan (Department of Food and Nutrition, Kyung Hee University) ;
  • Kim, Dong-Hyun (Department of Food and Nutrition, Kyung Hee University)
  • Published : 2003.10.01
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Abstract

Panax ginseng C.A. Meyer (Family Araliaceae) was treated at low ($60^{\circ}C$, LT), mild ($100^{\circ}C$, MT) and high ($120^{\circ}C$, HT) temperatures, some components (panaxytriol, ginsenosides and polysaccharides) were isolated, and their inhibitory effects on growth, infection and VacA vacuolation of Helicobacter pylori (HP) were investigated. The molecular weights of polysaccharides were decreased according to the increasing processed temperature. Ginseng polysaccharides inhibited the HP infection into KATO III cells, but did not inhibit HP growth and VacA vacuolation of HeLa cells. (omitted)

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