Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Antiallergic Activity of Ginsenoside $R_{h2}$

  • Park, Eun-Kyung (College of pharmacy, Kyung Hee University) ;
  • Choo, Min-Kyun (Department of Food and Nutrition, Kyung-hee University) ;
  • Kim, Eun-Jin (Department of Food and Nutrition, Kyung-hee University) ;
  • Han, Myung-Joo (Department of Food and Nutrition, Kyung-hee University) ;
  • Kim, Dong-Hyun (Department of Food and Nutrition, Kyung-hee University)
  • Published : 2003.10.01
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Abstract

Ginseng (the root of Panax ginseng C.A $M_{EYER}$, family Araliaceae) is frequently used as a crude substance in Asian countries as a traditional medicine. The major components of ginseng are ginsenosides, which have been reported to show various biological activities including antiinflammatory activity and antitumor effect. In addition, Sugiyama et al. reported that ginsenoside Rg3 suppresses histamine release from mast cells due to stimulation with compound 48/80 in vitro. However, the antiallergic effects of ginsenoside Rh2, which is metabolized by human intestinal bacteria to ginsenoside Rg3, have not been studied. (omitted)

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