대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.140.3-141
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- 2003
Isoflavones extracted from Sophorae Fructus upregulate the growth factors, IGF-I and TGF-$\beta$ in MG-63 cells
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Joo, Seong-Soo
(Department of Immunology, College of Pharmacy, Chung-Ang University) ;
- Kang, Hee-Chul (Department of Immunology, College of Pharmacy, Chung-Ang University) ;
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Lee, Min-Won
(Department of Immunology, College of Pharmacy, Chung-Ang University) ;
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Choi, Young-Wook
(Department of Immunology, College of Pharmacy, Chung-Ang University) ;
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Lee, Do-Ik
(Department of Immunology, College of Pharmacy, Chung-Ang University)
- 발행 : 2003.10.01
초록
Isoflavones have been a central subject in natural phytoestrogens found in Leguminosae. Their effects on bone formation and remodeling are an important turning point in that they can act like estrogen by binding on estrogen receptors on target cell surface. We, therefore, believed that isoflavones may be applied in estrogen deficiency disease such as osteoporosis in terms of estrogen replacement therapy (ERT). As commonly known, osteoporosis is one of hormonal deficiency diseases, especially in menopausal women. (omitted)
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