Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.133.1-133.1
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- 2003
Anti-diabetic effects and the evaluation of the immune response by F3-ESS from Cordyceps militaris in streptozotocin-induced diabetic mice
- Yun, Yun-Ha (Department of Pharmacy, Sahmyook University) ;
- Han, Shin-Ha (CM Biote) ;
- Lim, Hee-Jung (College of Pharmacy, Chung-Ang Univ.) ;
- Park, Eun-Jung (Dept. of Food Sci., Kangnung National Univ.) ;
- Son, Han-Shik (Dept. of Food Sci., Kangnung National Univ.) ;
- Lee, Seung-Jeong (Dept. of Food Sci., Kangnung National Univ.) ;
- Lee, M-In-Won (Dept. of Food Sci., Kangnung National Univ.) ;
- Lim, Yeong-Seon (Dept. of Food Sci., Kangnung National Univ.) ;
- Kim, Kyung-Jae (Dept. of Food Sci., Kangnung National Univ.)
- Published : 2003.10.01
Abstract
The antidiabetic effect of Cordyceps militaris (CM) extracted fractions, Fl (CCCA, Crude Cordycepin Containing Adenosine), F2 (Ethanol precipitation), F3 (Ethanol soluble supernatant) and F4 (fraction of through SK-1B), was investigated in streptozotocin (STZ)-diabetic mice. The results indicated F3 of CM lowered the blood glucose level than control in STZ-diabetic mice. High blood glucose was induced in mice by intraperitoneal injections of STZ (150 mg/kg). The F3-ESS, which contents cordycepin, strongly showed inhibitory actibity by 33.4% in mice loaded with starch (2 g/kg). (omitted)
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