Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.126.2-127
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- 2003
Compound-A inhibited the Reversed Cutaneous Anaphylaxis and Complement-Dependent Hypersensitivity
- Lee, Ji-Yun (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
- Kim, Youn-Joung (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
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Yoon, Mi-Yun
(Department of Pathophysiology, College of Pharmacy, Chung Ang University)
;
- Sim, Sang-Soo (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
- Kim, Chang-Jong (Department of Pathophysiology, College of Pharmacy, Chung Ang University)
- Published : 2003.10.01
Abstract
Effect of Compound-A, a phenylpropanoid isolated from Arctium lappa fruit, on the reversed cutaneous anaphylaxis (RCA) and complement-dependent hypersensitivity (CDH) were studied in SD male rats and ICR male mice, respectively. RCA and hemolysin (HY) titer test are related to reaction of Type II Hypersensitivity. Experiments were carried out to determine RCA as the edema of skin two hours after injection of 0.05 ml/site of anti-rat serum rabbit serum in SD rat. Drugs were orally administered one hour before antigen challenge. (omitted)
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