Genotoxic evaluation of Gyllus bimaculatus in 3 sets of mutagenicity tests

  • Ahn, Mi-Young (Dep. Seri & Entomol, Nat Inst of Agri Sci & Tech, RDA) ;
  • Pae, Hey-Jin (Div of Toxicol, School of Pharmacy, Sung Kyun Kwan University) ;
  • Lee, Byung-Mu (Div of Toxicol, School of Pharmacy, Sung Kyun Kwan University) ;
  • Ryu, Kang-Sun (Div of Toxicol, School of Pharmacy, Sung Kyun Kwan University)
  • Published : 2003.10.01

Abstract

The mutagenic potential of Gryllus bimaculatus was evaluated using the short-term genotoxicity tests including Ames, chromosome aberration and micronuclei tests. In salmonella typhimurium assay, G. bimaculatus did not show any mutagenic response in the absence or presence of S9 mix with TA98, TAl00, TA1535, and TA1537. In chromosome aberration test, G. bimaculatus did not show any significant effect on Chinese Hamster Ovary (CHO) cells compared with control. (omitted)

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