Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.118.2-118.2
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- 2003
Fatal cases related to propofol
- Choi, Hye-Young (National Institute of Scientific Investigation) ;
- Choi, Hwak-Yung (National Institute of Scientific Investigation) ;
- Lee, Ju-Seon (National Institute of Scientific Investigation) ;
- Woo, Sang-Hee (National Institute of Scientific Investigation) ;
- Park, Yoo-Sin (National Institute of Scientific Investigation)
- Published : 2003.10.01
Abstract
Propofol(2, 6-diisopropylphenol) is rapid, short-acting intravenous anaesthetic agent. It is used for the induction and maintenance of general anaesthesia or sedation. The recommended doses are 2-2.5mg/kg given as a titration infusion over about 30min to achieve anaesthesia. Recently, we encountered 4 fatalities related to propofol. One death is a suicide by self-administered of propofol and the others are therapeutic misadventures during surgical care. The propofol level in the blood and tissues were determined by gas chromatographic analysis with mass spectral detection. (omitted)
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