대한약학회:학술대회논문집 (Proceedings of the PSK Conference)

대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Antitumor effect of Ginsenoside Rh2 and $\beta$-glucan in mice

  • Lee, Chang-Hwan (Dept. of Hygienic Chemistry, College of Pharmacy, Kyung Hee University) ;
  • Shim, Kyoo-Jung (Dept. of Hygienic Chemistry, College of Pharmacy, Kyung Hee University) ;
  • Kim, Yun-Young (Dept. of Hygienic Chemistry, College of Pharmacy, Kyung Hee University) ;
  • Choung, Se-Young (Dept. of Hygienic Chemistry, College of Pharmacy, Kyung Hee University)
  • 발행 : 2003.10.01
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초록

In the present study, we investigated the antitumor effects of Ginsenoside Rh2 and $\beta$-glucan using an experimental metastatic mouse model intravenously injected with B 16 melanoma F10 cells. Oral administration to various concentration of $\beta$-glucan (50mg/kg, l00mg/kg and 200mg/kg) dose-dependently reduced the lung-metastatic potential of metastatic BI6 melanoma F10 cells in syngenic mice. At same dose, Ginsenoside Rh2(50mg/kg) has more antitumor effect than $\beta$-glucan(50mg/kg). (omitted)

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