대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.77.1-77.1
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- 2003
Effects of DW-286a, a fluoroquinolone antibiotic agent, on hERG channel currents expressed in CHO cells
- Kim, Eun-Joo (Korea Institute of Toxicology, KRICT) ;
- Kim, Ki-Suk (Korea Institute of Toxicology, KRIC) ;
- Shin, Won-Ho (Korea Institute of Toxicology, KRIC) ;
- Seo, Joung-Wook (Korea Institute of Toxicology, KRIC) ;
- Choi, Gyu-Kap (Korea Institute of Toxicology, KRIC) ;
- Park, Eun-Kyung (Korea Institute of Toxicology, KRIC) ;
- Hwang, Ji-Yoon (Korea Institute of Toxicology, KRIC) ;
- Han, Sang-Seop (Korea Institute of Toxicology, KRICT)
- 발행 : 2003.10.01
초록
Prolongation of the QT interval may result in a potentially dangerous arrhythmia. The most commonly proposed mechanism for QT interval prolongation(LQT) by pharmaceuticals is inhibition of the rapid delayed rectifier potassium channel (I
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