대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.70.2-71
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- 2003
Characterization of Muations in DNA Gyrase and Topoisomerase IV Involved in Resistant Mutants to DW-286a, a Novel Quinolone Antibiotic, in Streptococcus pneumoniae
- Seol, Min-Jeong (Division of Life & Food Sciences, Handong Global University) ;
- Kim, Hyun-Joo (Division of Life & Food Sciences, Handong Global University) ;
- Park, Hee-Soo (Division of Life & Food Sciences, Handong Global University) ;
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Kwak, Jin-Hwan
(Division of Life & Food Sciences, Handong Global University)
- 발행 : 2003.10.01
초록
Quinolone resistance in Streptococcus pneumoniae is related to mutations in the DNA gyrase and topoisomerase IV genes. DW-286a displayed potent activity against S. pneumoniae C9211 (MIC, 0.015
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