Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Identification of urinary metabolite(s) of CKD-712 by gas chromatography/mass spectrometry in rats

  • Jean, Hee-Kyung (Toxicology Laboratory, Korea Institute of Science ＆ Technology) ;
  • Choi, Hae-Yeon (Toxicology Laboratory, Korea Institute of Science ＆ Technolog) ;
  • Kim, Youn-Jung (Toxicology Laboratory, Korea Institute of Science ＆ Technolog) ;
  • Kwon, Oh-Seung (Toxicology Laboratory, Korea Institute of Science ＆ Technolog) ;
  • Ryu, Jae-Chun (Toxicology Laboratory, Korea Institute of Science ＆ Technology)
  • Published : 2003.04.01
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Abstract

Examination was made of the urinary metabolite(s) of CKD-712, which is a chiral compound, named S-YS49 derived from higenamine (one component of Aconite spp.) derivatives. First of all. to analyze the metabolite(s) of CKD-712, a simple and sensitive detection method for CKD-712 was developed by using gas chromatography-mass spectrometry(GC/MS). (omitted)

Keywords