Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.313.2-314
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- 2003
The pharmacokinetics of tramadol hydrochloride in Korean healthy volunteers
- Choi, Young-Wook (College of Pharmacy, Chungang University) ;
- Lee, Hee-Joo (Seoul Clinical Laboratorie) ;
- Han, Sang-Beom (College of Pharmacy, Dongduk Women′s University) ;
- Chun, In-Koo (College of Pharmacy, Chosun University) ;
- Gwak, Hye-Sun (College of Pharmacy, Chosun University)
- Published : 2003.04.01
Abstract
This study was conducted to investigate the pharmacokinetic characteristics of a synthetic opioid, Tridol\ulcornerCapsule (tramadol hydrochloride from Yuhan Pharmaceutical Co., Ltd., Korea) in 24 healthy Korean volunteers after a single dose administration. The volunteers received two capsules of 50 mg dose. Plasma samples were obtained over a 24-hour interval, and tramadol concentrations were obtained over a 24-hour intervalm and tramadol concentrations were determined by validated HPLC methods with a fluorescence detector. (omitted)
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