대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.296.1-296.1
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- 2003
EXTERNAL GEL FORMULATIONS OF PROSTAGLANDIN E1 ETHYL ESTER
- Kim, Hee-Kyu (College of Pharmacy, Chung-Ang University) ;
- Kim, Jong-Seok (Gu-ju Pharm. Co., Lt) ;
- Lee, Sang-Kil (College of Pharmacy, Yeung-Nam University) ;
- Yang, Sung-Woon (College of Pharmacy, Yeung-Nam University) ;
- Lee, Ji-Eun (College of Pharmacy, Yeung-Nam University) ;
- Choi, Han-Gon (College of Pharmacy, Yeung-Nam University) ;
- Yong, Chulsoon (College of Pharmacy, Yeung-Nam University) ;
- Choi, Young-Wook (College of Pharmacy, Yeung-Nam University)
- 발행 : 2003.04.01
초록
Purpose. External gel formulations of prostaglandin E1 ethyl ester (PGE1-EE), a prod rug of PGE1 as a therapeutic agent for erectile dysfunction, were tried and evaluated by in vitro skin penetration characteristics and in vivo pharmacodynamic effects in cat. Method. The in vitro skin penetration was performed with Franz diffusion cell and examined in aspects of alcohol/polyol ratios and various enhancers. (omitted)
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