Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.294.2-295
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- 2003
Tyrosinase inhibitory effect of gentisic acid derivatives
- Lee, Yeon-Jung (College of Pharmacy, Pusan National University) ;
- Yoon, Sung-Il (Department of Biotechnology, Dongseo University) ;
- Kim, Jung-Sun (Department of Biotechnology, Dongseo University) ;
- Lee, Chi-Ho (College of Pharmacy, Pusan National University) ;
- Kim, Dae-Duk (College of Pharmacy, Pusan National University)
- Published : 2003.04.01
Abstract
Gentisic acid, a skin-whitening agent, is known to possess tyrosinase inhibition activity. In order to develop an effective skin-whitening agent, hydroquinone derivatives in which the carboxylic acid moiety of gentisic acid was replaced with various functional groups, were selected and evaluated for their ability to inhibit tyrosinase activity as well as to inhibit melanin release. (omitted)
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