Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.282.1-282.1
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- 2003
Determination of Glimepiride in Human Plasma by LC-MS/MS
- Kim, Ho-Hyun (Seoul Medical Science Institute (SCL)) ;
- Roh, Hyeong-Jin (BioCore Co. Ltd) ;
- Lee, Hee-Joo (BioCore Co. Ltd) ;
- Han, Sang-Beom (BioCore Co. Ltd.)
- Published : 2003.04.01
Abstract
This study established a sensitive novel Quantification method for detecting glimepiride in human plasma using LC-MS/MS for pharmacokinetic studies. The mobile phase used after degassing was composed of 10 mM ammonium acetate and acetonitrile (20:80, pH 3.0), with flow rate of 200uL/min. One mL plasma were pipetted into glass tubes and spiked with 0.1 mL of internal standard solution. (omitted)
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