Chiral Separation of Aromatic Amino Acids by Capillary Electrophoresis using (+)-18-crown-6 tetracarboxylic acid and (-)-18-crown-6 tetracarboxylic acid as Chiral Selectors

Recently, particular attention has been paid to the chiral separation of amino acid enantiomers because of their different biological activities. Hence, the high optical purity of aromatic amino acids is critical because of their important functions in the central nervous system. For the accurate chiral discrimination. we attempted to exploit the crosschecking each enantiomeric migraion orders of aromatic amino acids measured using (+)-18C6H4TA and (-)-18C6H4TA as the chiral selectors under pH 2.0, tris/citric acid buffer.