Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Screening of Cytotoxicity of Hexane Extracts from Cornis fructus

  • Chun, Hyun-Ja (Division of Natural Science, Department of Herbal Rresources, Wonkwang University) ;
  • Choi, Won-Hyung (Division of Natural Science, third Medicine, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, Jeong-Ho (Department of Cosmetics, Wonkwang Health Science Colleg) ;
  • Lee, Ji-Su (Department of Cosmetics, Wonkwang Health Science Colleg) ;
  • Yang, Hyun-Ok (Department of Cosmetics, Wonkwang Health Science Colleg) ;
  • Baek, Seung-Hwa (Department of Cosmetics, Wonkwang Health Science College)
  • Published : 2003.04.01
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Abstract

Cornis fructus were extracted by successive extraction and then fractionated with hexane extract to get active fractions. This study was performed to determine the cytotoxic effect of hexane extract from Cornis fructus on NIH 3T3 fibroblasts and cancer cell lines using MTT assay. Hexane extract showed cytotoxic effect against A549, B16 melanoma and MDA-MB-231. Further fractionation with hexane extract were performed to obtain effective fraction, fraction 3 showed the cytotoxic effect against A549 and MDA-MB-231 cell line.

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