Preventive Agents against Sepsis and New Phenylpropanoid Glucosides from the Fruits of Illicium verum

  • Lee, Sung-Won (College of Pharmacy, Yeungnam University) ;
  • Li, Gao (Institute of Natural Sciences, Yeungnam University) ;
  • Lee, Kyong-Sun (Department of Pharmacology, Hallym University College of medicine, Institute of Natural medicin) ;
  • Jung, Jun-Sub (Department of Pharmacology, Hallym University College of medicine, Institute of Natural medicin) ;
  • Xu, Ming-Lu (Department of Pharmacology, Hallym University College of medicine, Institute of Natural medicin) ;
  • Seo, Chang-Seob (Department of Pharmacology, Hallym University College of medicine, Institute of Natural medicin) ;
  • Song, Dong-Keun (Department of Pharmacology, Hallym University College of medicine, Institute of Natural medicin) ;
  • Son, Jong-Keun (Department of Pharmacology, Hallym University College of medicine, Institute of Natural medicine)
  • Published : 2003.04.01

Abstract

The bioassay-guided fractionation of preventive agents against lethality due to septic shock from the fruits of Illicium verum lead to the isolation of two known racemic mixtures of phenylpropanoids (1 and 2), along with two known phenylpropanoid glucosides (3 and 5) and two new phenylpropanoid glucosides (4 and 6). Their chemical structures were elucidated on the basis of spectroscopic studies. (omitted)

Keywords