Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

The DNA Strand-Scission principles of Mucunar birdwoodiana

  • Han, Ah-Reum (Natural Products Chemistry Laboratory, College of Pharmacy, Ewha Womans University) ;
  • Park, Go-Wooni (Natural Products Chemistry Laboratory, College of Pharmacy, Ewha Womans University) ;
  • Je, Kang-Hoon (Natural Products Research Institute, Seoul National University) ;
  • Mar, Woong-Chon (Natural Products Research Institute, Seoul National University) ;
  • Seo, Eun-Kyoung (Natural Products Research Institute, Seoul National University)
  • Published : 2003.04.01
Download PDF
⟨ Previous Next ⟩

Abstract

During our research program to find DNA strand-scission agents from higher plants, the MeOH extracts of the wood bark of Mucunar birdwoodiana Tutcher. (Leguminosae) exhibited the most potent activity with an IC$\^$50/ value of 4.9 $\mu\textrm{g}$/$m\ell$. Thus, detailed laboratory investigation was performed, and led to the isolation of the known compounds, catechin(1) and epicatechin(2) as the active principles. (omitted)

Keywords