Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.252.3-252.3
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- 2003
HANTZSCH DIHYDROPYRIDINE: AN EFFECTIVE AND CONVENIENT REGIOSELECTIVE REDUCING AGENT FOR 5-BENZYLIDENE-2,4- THIAZOLIDINEDIONE DERIVATIVES
- Lee, Hong-Woo (Chemical Process Development Lab, Chong Kun Dang Research Institute) ;
- Kim, Bok-Young (Chemical Process Development Lab, Chong Kun Dang Research Institut) ;
- Ahn, Joong-Bok (Chemical Process Development Lab, Chong Kun Dang Research Institut) ;
- Son, Hoe-Joo (Chemical Process Development Lab, Chong Kun Dang Research Institut) ;
- Lee, Jae-Wook (Chemical Process Development Lab, Chong Kun Dang Research Institut) ;
- Ahn, Soon-Kil (Chemical Process Development Lab, Chong Kun Dang Research Institut) ;
- Hong, Chung-Il (Chemical Process Development Lab, Chong Kun Dang Research Institute)
- Published : 2003.04.01
Abstract
An effective and convenient regioselective reduction of 5-benzylidene 2,4-thiazolidinedione derivatives to the corresponding 5-benzyl 2,4-thiazolidinedione derivatives has been accomplished using 3,5-dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine (Hantzsch dihydropyridine ester: HEH) with silica gel as an acid catalyst in a good yield.
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