A Model Study toward the Synthesis of Xestoquinone and Halenaquinone

  • Ahn, Chan-Mug (Dept. of Basic Sciences, Institute of Basic Medical Science, Yonsei University Wonju College of Medicine) ;
  • Woo, Ho-Bum (Dept. of Basic Sciences, Institute of Basic Medical Science, Yonsei University Wonju College of Medicine)
  • Published : 2003.04.01

Abstract

A strategy for synthesis of the furan-fused tetracyclic core of xestoquinone and halenaquinone was explored through a model study. Methyl 8-oxo-4-methyl-4-phenyl-2,7-nonadiynoate was prepared from hydratroponitrile and 3-butyn-1-ol as starting materials. The intramolecular cycloaddition of this intermediate as a key step will be involved.

Keywords