Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.237.3-238
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- 2003
The Synthesis of Novel Cyclobutyl Nucleoside as Potential Antiviral Agents
- Wi, Hyung-Hwa (Department of Medicinal Chemistry, College of Pharmacy, Chonnam National University) ;
- Kook, Min-Cheol (Department of Medicinal Chemistry, College of Pharmacy, Chonnam National University) ;
- Choi, Bo-Gil (Department of Medicinal Chemistry, College of Pharmacy, Chonnam National University)
- Published : 2003.04.01
Abstract
Carbonucleosides has extensively been studied as a promising anti-viral agents having chemical and metabolical stability. As yet there are no rules relating the structures of carbocyclic nucleosides to their therapeutic activity. although trends among certain kinds of structure have been tentatively put forward. In our research program for discovery of anti-viral drugs, the novel cyclobutyl nucleosides can be expected to be potential antiviral drugs as analogues of cyclobut-A, anti-HBV agent. (omitted)
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