Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Reagentselective reduction of 25(R)-1,4,6-spirostatrien-3-one

  • Ma, Eun-Sook (Department of Pharmacy, Catholic University of Daegu) ;
  • Kim, Hak-Soon (Department of Pharmacy, Catholic University of Daeg) ;
  • Kim, Eun-Jung (Department of Pharmacy, Catholic University of Daeg) ;
  • Jung, Won-Young (Department of Pharmacy, Catholic University of Daeg) ;
  • Choi, Tae-Young (Department of Pharmacy, Catholic University of Daegu)
  • Published : 2003.04.01
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Abstract

Spicatoside A and spicatoside B were isolated from Liriopis tuber. Spicatoside A has anticancer activity and it is composed of 1 ${\beta}$-hydroxy diosgenin and trisaccharides. Spicatoside B has the preventive effect of diabetes mellitus and also has 1 ${\beta}$-hydroxy derivatives, which is clevaged the ether linkage of F ring of diosgenin. Therefore, selective synthesis of 1 ${\beta}$-hydroxydiosgenin is required. (omitted)

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