Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Involvement of MAPKs in GDNF-induced Proliferation and Migration in Hs683 Glioma Cells

  • Song, Hyun (College of Pharmacy, Duksung Women′s University) ;
  • Moon, A-Ree (College of Pharmacy, Duksung Women′s University)
  • Published : 2003.04.01
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Abstract

Glial cell-derived neurotrophic factor (GDNF) is a potent neurotrophic factor that enhances survival of midbrain doparminergic neuron. GDNF and its receptors are widely distributed in brain and are believed to be involved in the control of neuron survival and differentiation. GDNF increased proliferation and migration of Hs683 human giloma and C6 rat giloma cells in a dose-dependent manner. (omitted)

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