Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.221.2-222
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- 2003
Alteration of Cellular Adhesion Molecules during Aging and Their Modulation by Calorie Restriction
- Zou, Yani (College of Pharmacy, Pusan National University) ;
- Kim, You-Jung (Department of Cosmetology, Pusan Women′s Colleg) ;
- Kim, Ji-Young (Department of Cosmetology, Pusan Women′s Colleg) ;
- Kang, Dae-Yoen (Department of Cosmetology, Pusan Women′s Colleg) ;
- Kim, Nam-Deuk (Department of Cosmetology, Pusan Women′s Colleg) ;
- Lee, Kyung-Hee (Department of Cosmetology, Pusan Women′s Colleg) ;
- Chung, Hae-Young (Department of Cosmetology, Pusan Women′s College)
- Published : 2003.04.01
Abstract
Expressions of cellular adhesion molecules (CAMs) are closely related to the formation of early atherosclerosis, an age-dependent vascular disorder. However. previous research provided only limited and conflicted reports on age-related alterations of CAMs' expressions and even much less is known the modulation of CAMs by calorie restriction (CR), In this study, expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), E-selectin, P-selectin and platelet/endothelial cell adhesion molecule-1 (PECAM-1) in aorta and kidney were investigated by western blot and immuno-histochemical stain utilizing ad libitum (AL) and CR rat. (omitted)
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