대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.218.2-219
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- 2003
Characterization of 2-hydroxymuconic semialdehyde dehydrogenase from Burkholderia cepacia G4
- A. Matta Reddy (College of Pharmacy, Chungbuk National University) ;
- Min, Kyung-Rak (College of Pharmacy, Chungbuk National University) ;
- Kim, Young-Soo (College of Pharmacy, Chungbuk National University)
- 발행 : 2003.04.01
초록
2-Hydroxymuconic semialdehyde dehydrogenase catalyzes the conversion of 2-hydroxymuconic semialdehyde (HMS) to an enol form of 4-oxalocrotonate which is a step in the catechol-meta cleavage pathway. A tomC gene encoding 2-HMS dehydrogenase of Burkholderia cepacia G4, a soil bacterium that can grow on toluene, cresol, phenol or tricholoro ethylene, is identified in between catechol 2,3-dioxygenase gene and HMS hydrolase gene, its sequence is analysed and the enzyme is characterised. (omitted)
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