Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.216.1-216.1
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- 2003
Sauchinone, a Lignan from Saururus chinensis, Inhibits Staurosporine-induced Apoptosis in C6 Rat Glioma Cells
- Song, Hyun (College of Pharmacy, Duksung Women′s University) ;
- Kim, Young-Choong (College of Pharmacy, Seoul National University) ;
- Moon, A-Ree (College of Pharmacy, Duksung Women′s University)
- Published : 2003.04.01
Abstract
Neuronal apoptosis may contribute to the pathological neuronal loss in certain disease states such as neurodegenerative diseases. Staurosporine (ST), a nonselective protein kinase inhibitor, has been shown to induce apoptosis in a variety of cells including nerve cell lines. In this study, we investigated the neuroprotective effect of sauchinone, which is a unique lignan from Sauchinone Chinensis, on ST-induced apoptosis in C6 rat glioma cells. (omitted)
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