대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.215.2-216
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- 2003
Antitumor activity of organic compounds isolated from Korean mistletoe
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Yoo, Yung-Choon
(College of Medicine, Konyang University)
;
- Song, Kyung-Sik (Natural Product Chemistry Lab) ;
- Lee, Kyung-Bok (Dept. of Agric. Chem., Kyungbook University) ;
- Lee, Hoi-Young (Inst. of Biomedical Research, Handong University) ;
- Kim, Jong-Bae (Inst. of Biomedical Research, Handong University)
- 발행 : 2003.04.01
초록
Velutin and betulinic acid were isolated as a cytotoxic principle from the dichloromethane extract of Korean mistletoe (Viscum album var. coloratum) by repeated silicagel chromatography and recrystallization. In in vitro analysis of cytotoxic activity using NIH-3T3 cells, dichloromethane extract of Korean mistletoe was shown to be highly cytotoxic against tumor cells. And we obtained active compound (reffered to VD-2 and VD-6) from the dichloromethane extract. (omitted)
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