Immuno-modulation Effects of Ginsenoside Rg1 in Rat microglia

  • Joo, Seong-Soo (Department of Immunology, College of Pharmacy, Chung-Ang University) ;
  • Won, Tae-Joon (Department of Immunology, College of Pharmacy, Chung-Ang University) ;
  • Lee, Do-Ik (Department of Immunology, College of Pharmacy, Chung-Ang University)
  • Published : 2003.04.01

Abstract

Microglial cell is a monocyte involved in the brain, which acts for a primary immune reaction and phagocytosis. Microglia has also been considered to have a great role in AD pathogenesis due to its intact inflammatory and phagocytic responses against foreign invaders. In the study, we tried to investigate the modulation of activation of microglia using Rg1, a class of ginsenoside from red ginseng. which are known to protect neuron cells. (omitted)

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