Inhibitory Action of Cinnamic Acid Derivatives on Reversed Cutaneous Anaphylasis and Hemolysin Titer

  • Kim, Tae-Doo (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Lee, Ji-Yun (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Kim, Youn-Joung (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Lee, Jin-Hee (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Sim, Sang-Soo (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Kim, Chang-Jong (Department of Pathophysiology, College of Pharmacy, Chung Ang University)
  • Published : 2003.04.01

Abstract

Cinnamic acid derivatives(CAD) originating from vegetable kingdom have some biological activity. Effect of CAD on reversed cutaneous anaphylaxis (RCA) and hemolysin (HY) titer were studied in rats. Experiments were carried out to determine RCA as the skin edema induced at 2 hours after injection of 0.05 $m\ell$/site of anti-rat serum rabbit serum. Drugs were orally administered at one hour before antigen challenge. (omitted)

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