Effect of Trolox C in the Vasoregulatory Gene Expression during Hepatic Ischemia/Reperfusion

  • Eum, Hyun-Ae (Colleage of Pharmacy, Sungkyunkwan University) ;
  • Lee, Sun-Mee (Colleage of Pharmacy, Sungkyunkwan University)
  • Published : 2003.04.01

Abstract

The present study was done to determine the effect of trolox C. a hydrophilic analogue of vitamin E, on hepatic injury, especially alteration in vasoregulatory gene expression during ischemia and reperfusion. Rats were subjected to 60 min of hepatic ischemia in vivo. Rats were treated intravenously with trolox C (2.5 mg/kg) or vehicle (PBS, pH 7.4), 5 min before reperfusion. (omitted)

Keywords