Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.184-184
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- 2003
TERT mRNA expression is up-regulated in MCF-7 cells and mouse mammary gland organ culture (MMOC) system by endosulfan treatment
- Je, Kang-Hoon (College of Veterinary Medicine and Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
- Nam, Kung-Woo (College of Veterinary Medicine and Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
- Kim, Ki-Nam (College of Veterinary Medicine and Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
- Cho, Myung-Haing (College of Veterinary Medicine and Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
- Mar, Woong-Chon (College of Veterinary Medicine and Natural Products Research Institute, College of Pharmacy, Seoul National University)
- Published : 2003.04.01
Abstract
Endosulfan is one of the organochlorine pesticides, well-known endocrine disruptors (EDs). Many EDs show the estrogenic effect. Estrogen is a group of hormones that play an important role in mammary gland function and implicated in mammary carcinogenesis. In the present study. using mouse mammary gland organ culture (MMOC) system. we studied the the effects of endosulfan on nodule like alveolar lesion (NLAL) formation in the mouse mammary gland development. (omitted)
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