Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Effect of Solanum Iyratum Extract on Dimethylnitrosamine-Induced Liver Damage in Rats

  • Shin, Mi-Ok (College of Pharmacy, Pusan National University) ;
  • Park, Jong-Hee (Department of Anatomy, College of Medicine, Pusan National University) ;
  • Yoon, Sik (Department of Anatomy, College of Medicine, Pusan National University) ;
  • Moon, Jeon-Ok (Department of Anatomy, College of Medicine, Pusan National University)
  • Published : 2003.04.01
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Abstract

Solanum lyratum (Solanaceae) has been used as a traditional analgesic, antipyretic and hepatoprotective agents in Korea. In this study, we investigated the hepatoprotective effect of ethylacetate extract of Solanum lyratum (SL) on the dimethylnitrosamine (DMN)-induced liver damage in rats. Oral administration of SL (150, 300 mg/kg daily for 4 weeks) into the DMN-treated rats remarkably prevented the elevation of serum alanine transaminase, aspartate transaminase and alkaline phosphatase levels. (omitted)

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