Cytotoxic Activity of Extracts from Houttuynia cordata

  • Lee, Jeong-Ho (Department of Third Medicine, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, Ki-Nam (Department of Third Medicine, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Ryu, Hyeong-Won (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lim, Jin-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, In-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Chun, Hyun-Ja (Division of Natural Science, Wonkwang University) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • Published : 2003.04.01

Abstract

This study was carried out to evaluate cytotoxic effects of Houttuynia cordata THUNB extracts on A549 (lung cancer), MDA-MB231 (breast cancer), SNU-C4 (colon cancer) and B16 (mouse melanoma) cell lines. We have determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide (MTT) assay. The 150 $\mu$g/$m\ell$ concentration of methanol extract (63.81 %) of Houttuynia cordata THUNB was shown significantly antitoxic activity on A549 cell lines. (omitted)

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