Effects of Platycodi Radix on Hepatic Fibrosis in Rats

  • Lee, Kyung-Jin (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun Uni.) ;
  • Kim, Young-Sup (Korea Research Institute of Chemical Technology) ;
  • Ryu, Si-Yung (Korea Research Institute of Chemical Technology) ;
  • Chung, Young-Chul (Division of Food Science, Jinju International Uni) ;
  • Choi, Chul-Yung (Division of Food Science, Jinju International Uni) ;
  • Cho, Young-Soo (Department of R&D, JangsaengDoraji Co. Ltd.) ;
  • Jeong, Hye-Gwang (Department of Pharmacy, College of Pharmacy, Research Center for Proteineous Materials, Chosun Uni.)
  • Published : 2003.04.01

Abstract

Herbal medicines are increasingly being utilized to treat a wide variety of disease processes. We previously reported that aqueous extract from the roots of Platycodon grandiflorum A. DC (Campanulaceae), Changkil (CK), had hepatoprotective effects against acetaminophen induced liver injury. In the present study, we assayed the preventive and therapeutic effects of CK on experimental hepatic fibrosis induced by dimethylnitrogamine or carbon tetrachloride in rats. (omitted)

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