Induction of Apoptosis by N-nitrosocarbofuran, via Cytochrome c-Mediated Activation of Caspase-3 protease

  • Lee, Bang-Wool (College of Pharmacy and Medicinal Resources Research Center WonKwang University) ;
  • Oh, Seon-Hee (College of Pharmacy and Medicinal Resources Research Center WonKwang University) ;
  • Lee, Byung-Hoon (College of Pharmacy and Medicinal Resources Research Center WonKwang University)
  • 발행 : 2003.04.01

초록

Carbofuran(CF) is one of the most widely used carbamate pesticides in the world applied for insect and nematode control. Due to its widespread use in agriculture and households, contamination of food, water, and air has become serious, and consequently adverse health effects are inevitable in humans, animals, wildlife and fish, it has reported that CF alone or in combination with other carbamate insecticides influences the level of reproductive and metabolic hormones such as thyroxine and corticosterone, and results in impairment of endocrine, immune behavioral functions. (omitted)

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