The protective and antioxidant effect of Solanum lycopersicum extract in liver fibrosis induced rats

  • Oh, Se-Mi (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Park, Jun-Ho (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee, Sang-Hee (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Kim, Hee-Seok (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Kim, Ki-Young (Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Andrea, Mattes (Professional Graduate School of Oriental Medicine, Wonkwang University)
  • Published : 2003.04.01

Abstract

The adducts of lipid peroxidation and related aldehydic end are mediators of chronic poisoning and affect the development of chronic liver damage leading to fibrosis and cirrhosis. Substances delayed or suppresed lipid peroxidation could have an antioxidant and protective effect in liver disease. In this study, it was attempted to find out above mentioned effect of Solanum lycopersicum investigated in CCl4 induce liver fibrosis model. (omitted)

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