Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Alternation and significance of calcium signalings through ryanodine receptor in neuronal cell death

  • Hwang, In-Young (College of Phamacy, Chungbuk National University) ;
  • Lee, Sang-Min (College of Phamacy, Chungbuk National University) ;
  • Lee, Yoot-Mo (College of Phamacy, Chungbuk National University) ;
  • Kim, Su-Jin (College of Phamacy, Chungbuk National University) ;
  • Lee, Myung-Koo (College of Phamacy, Chungbuk National University) ;
  • Oh, Ki-Wan (College of Phamacy, Chungbuk National University) ;
  • Hong, Jin-Tae (College of Phamacy, Chungbuk National University)
  • Published : 2003.04.01
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Abstract

Pathophysiological elevation of intracellular calcium concentration ([$Ca^{2+}$]$_i$) in the neuron has been considered as an important responsible factor in the neuronal cell damages. However, the mechanism of increase of [$Ca^{2+}$]$_i$ through ryanodine receptor (RyR), the relationship between [$Ca^{2+}$]$_i$ level and cell damages have not been fully demonstrated. (omitted)

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