Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Btg-1 Induction by Oxidative Stress

  • Cho, Il-Je (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Lee, Song-Jin (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Kim, Sang-Geon (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
  • Published : 2003.04.01
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Abstract

B cell translocation gene-1 (Btg-1), originally discovered from chromosomal translocation in chronic B-cell lymphocytic leukemia. belongs to the APRO family. Btg-1 exhibit antiproliferative function. being expressed during the $G_{0}/G_{1}$ transition phase of cell cycle. Btg-1 is fully expressed in quiescent and differentiated cells. while the protein expression decreases as the cell progresses through the cell cycle. (omitted)

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