$\beta$-EUDESMOL CAUSES VASODILATORY EFFECT IN THE NORMOTENSIVE RAT

  • Lim, Dong-Yoon (Department of Pharmacology, College of Medicine, Chosun University) ;
  • Shin, Hye-Gyeong (Department of Pharmacology, College of Medicine, Chosun University)
  • Published : 2003.04.01

Abstract

$\beta$-Eudesmol is one of various compounds derived from the bark of Magnolia obovata Thunberg, a medicinal plant. It has been shown that $\beta$-eudesmol also markedly alleviated muscle fasciculation, tremor and convulsion induced by diisopropylfluorophosphate and prolonged the time to death in mice (Chiou et al., 1995). Actually, the extract of magnolia bark has been shown to have depressant actions on the cental nervous system (Watanabe et al., 1973). (omitted)

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