Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.135.3-136
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- 2003
Enhancement of nerve growth factor production and release by buthanol fraction of Liriope platyphylla in C6 cells and rat cultured astrocyte
- Hur, Jin-Young (Department of Herbal Pharmacology, Graduate School of East-West Medical Science, Kyung Hee University) ;
- Lee, Pyeong-Jae (Department of Herbal Pharmacology, Graduate School of East-West Medical Science, Kyung Hee University) ;
- Kim, Jeong-Min (Department of Herbal Pharmacology, Graduate School of East-West Medical Science, Kyung Hee University) ;
- Kim, Ho-Cheol (Department of Herbal Pharmacology, Graduate School of East-West Medical Science, Kyung Hee University) ;
- Kim, Sun-Yeou (Department of Herbal Pharmacology, Graduate School of East-West Medical Science, Kyung Hee University)
- Published : 2003.04.01
Abstract
Liriope platyphylla (LP) Wang et Tang has been used for tonic, anti-tussive and expectorant in Korea. In the current study, we found that buthanol fraction of Liriope platyphylla-conditioned media of C6 and primary astrocyte induced the neurite outgrowth of PC 12 cells, which effect was reversed by addition of NGF-antibody. We demonstrated that buthanol fraction of Liriope platyphylla increased the expression and secretion of NGF through RT-PCR and ELISA. (omitted)
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