대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
- /
- Pages.132.1-132.1
- /
- 2003
Antitumor activity and 3D-Histoculture drug response assay of Novel trans- ditrifluoroacetato,malonato-1,4-butanediamine Pt(IV) complex, K104
- Kwon, Young-Ee (Drug Discovery Institute, STC Life Science Center, College of Pharmacy Dongduk Women′s University) ;
- Kim, Kuk-Hwan (Drug Discovery Institute, STC Life Science Center, College of Pharmacy Dongduk Women′s University) ;
- Oh, Bong-Un (Drug Discovery Institute, STC Life Science Center, College of Pharmacy Dongduk Women′s University) ;
- Kim, Kap-Joon (Drug Discovery Institute, STC Life Science Center, College of Pharmacy Dongduk Women′s University)
- 발행 : 2003.04.01
초록
Novel trans-ditrifluoroacetato, malonato-1, 4-butanediamine Pt(IV) complex, K104 was synthesized as a chemotherpeutic. The cytotoxicity of K104 against various human cancer cell lines were evaluated by MTS assay in vitro. The IC50 values of K104 ranged 15.83-25.83
키워드