대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.107-108
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- 2003
Multiple Roles of Phospholipase D in Growth Factor Signaling
- Ryu, Sung-Ho (Division of Molecular and Life Sciences, Pohang University of Science & Technology)
- 발행 : 2003.04.01
초록
The epidermal growth factor (EGF) is an important signaling ligand for the mitogenesis of many cells. The EGF receptors use signaling molecule multicomplexes and dynamic protein networks for the transmission and amplification of the signals as well as for the regulation of the cellular responses. EGF signaling has been reported to be enhanced in various tumors by the overexpressed EGF receptor and/or the mediators such as phospholipase C-
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