Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.77-77
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- 2003
Aminoacyl-tRNA Synthetase Cofactor, p43, is a Novel Cytokine and an Immune Modulator: Implications for Autoimmune Diseases and Bacterial Infections
- Kim, Sung-Hoon (Center for ARS Network, College of Pharmacy, Seoul National University)
- Published : 2003.04.01
Abstract
p43 is a protein with complex biological activities. It is first found as a protein associated with macromolecular tRNA synthetase complex. Within this complex, p43 specifically interacts with arginyl-tRNA synthetase to help the substrate tRNA binding to the enzyme. It is also necessary for the cellular stability of arginyl-tRNA synthetase and the molecular association of a few complex-forming tRNA synthetases. (omitted)
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