대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-1
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- Pages.74-74
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- 2003
Molecular Mechanism for Methylmercury-induced Toxicity in Kidney and Brain Cells
- Kim, Dae-Kyong (Department of Environmental and Health Chemistry, College of Pharmacy, Chung-Ang University) ;
- Kang, Mi-Sun (Department of Environmental and Health Chemistry, College of Pharmacy, Chung-Ang University) ;
- Jeong, Ju-Yeon (Department of Environmental and Health Chemistry, College of Pharmacy, Chung-Ang University) ;
- Jung, Sung-Yun (Department of Environmental and Health Chemistry, College of Pharmacy, Chung-Ang University) ;
- Seo, Ji-Heui (Department of Environmental and Health Chemistry, College of Pharmacy, Chung-Ang University) ;
- Joseph V.Bonventre (Renal Unit, Massachusetts General Hospital-East, Havard Medical School)
- 발행 : 2003.10.01
초록
Methylmercury (MeHg) is a ubiquitous environmental toxicant that can be exposed to humans by ingestion of contaminated food including fish and bread. MeHg has been suggested to exert its toxicity through its high reactivity to thiols, generation of arachidonic acid and reactive oxygen species (ROS), and elevation of intracellular
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