Mechanism for Arsenic-Induced Alteration of Contractility in Blood Vessels

  • Lee, M.Y. (College of Pharmacy, Seoul National University) ;
  • Chung, S.M. (College of Pharmacy, Seoul National University) ;
  • Bae, O.N. (College of Pharmacy, Seoul National University) ;
  • Chung, J.H. (College of Pharmacy, Seoul National University)
  • 발행 : 2003.10.01

초록

Several epidemiological studies suggested that arsenic exposure was strongly correlated with the development of cardiovascular disease such as hypertension. In order to examine whether arsenic affects vasomotor tone in blood vessels, we investigated the effect of arsenic on agonist-induced vasorelaxation using the isolated rat aortic rings in in vitro organ bath system. (omitted)

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