Kynurenic Acid (KYNA) Attenuates Oxidative Stress and Mitochondrial damage in 6-OHDA-induced Dopaminergic Neuronal Cell Death

  • 발행 : 2003.10.01

초록

Kynurenic acid (KYNA), tryptophan metabolite is known to have cell protective effect against various insults in the brain. But so far, the protective mechanism is largely unknown. In this study, we investigated how the KYNA exerts protective effect against 6-OHDA, a causative molecule of Parkinsonian syndrome, using SH-SY5Y cells. (omitted)

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