Phospholipids from Bombycis corpus and Their Neurotrophic Effects

  • Yeon Jung (Department of Sericulture and Entomology, National Institute Agricultural Science and Technology) ;
  • Kwon, Hak-Cheol (College of Pharmacy, SungkyunKwan University) ;
  • Cho, Se-Yeon (Department of Sericulture and Entomology, National Institute Agricultural Science and Technolog) ;
  • Cho, Ock-Ryun (College of Pharmacy, SungKyunKwan University) ;
  • Yang, Min-Cheol (College of Pharmacy, SungKyunKwan University) ;
  • Kim, Sun-Yeou (Korea and Graduate School of East-West Medical Scinces, Kyung Hee University) ;
  • Lee, Kang-Ro (College of Pharmacy, SungKyunKwan University)
  • 발행 : 2003.10.01

초록

This study was carried out to investigate active constituents of Bombysis corpus on the neurite outgrowth from PCl2 cells led to isolate three phospholipids (4 6) and three aromatic amines (13) were obtained from the methanol extract of Bombycis corpus. Based on spectral data, their structures have been elucidated as nicotiamide (1), cytidine (2), adenine (3), 1-O-(9Z-octadecenoyl)-2-O-(8Z, 11Z-octadecadienoyl)-sn-glycero-3-phosphorylcholine(4), 1, 2-di-O-hexadecanoyl-sn-glycero-3-phosphorylcholine(5) and 1, 2-di-O-9Z-octadecenoyl-sn-glycero-3-phosphorylcholine(6). (omitted)

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