Proceedings of the Korean Society of Sericultural Science Conference (한국잠사학회:학술대회논문집)

Korean Society of Sericultural Science (한국잠사학회)
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Evaluation of 1-DNJ extracted from Silkworm in GBV-B Infected Marmoset Hepatocytes

  • James R. Jacob (Dept. of Clinical Sciences, Coll. of Veterinary Medicine, Cornell Univ) ;
  • Yoo, Jung-Eun (Dept. of Life Science, The Univ. of Suwo) ;
  • Seong, Su-Il (Dept. of Life Science, The Univ. of Suwo) ;
  • Ryu, Kang-Sun (Dept. of Sericulture and Entomology, NIAST, RD) ;
  • Kim, Young-Ho (Dept. of Life Science, The Univ. of Suwon)
  • Published : 2003.04.01
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Abstract

Alpha-glucosidase inhibitor, 1-deoxynojirimycin, has been shown to eliminate the production of ER-budding viruses in the ER of host cell. This glucose-derived iminosugar derivative, 1-DNJ, has been largely purified from midgut of silkworm, Bombyx mori, Here, we have screened the antiviral activity in the GBV-B infected marmoset hepatocyte cell line. (omitted)

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